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更新于 6月30日

(Senior) Research Scientist in vitro pharmacology體外藥理

2-2.6萬(wàn)
  • 上海浦東新區(qū)
  • 5-10年
  • 碩士
  • 全職
  • 招1人

職位描述

新藥
Role Summary We seek a highly motivated In Vitro Scientist or Senior Scientist to drive the design, development, and validation of in vitro assays for drug discovery programs. The ideal candidate will have extensive hands-on experience in vitro assays including molecular biology and cellular assays, e.g. ELISA, western blot, FACS, qPCR, and mammalian cell culture. You will play a key role in advancing preclinical pipelines through rigorous in vitro data generation and mechanism exploration.
Key Responsibilities 1. Design, optimize, and validate in vitro assays to support target validation, lead optimization, and mechanism-of-action studies 2. Independently execute molecular & cellular assays: ELISA, Western blot, FACS, qPCR, high-content imaging 3. Maintain and utilize mammalian cell culture systems (primary and immortalized lines) 4. Analyze, interpret, and present data to cross-functional teams 5. Contribute to pre-clinical development studies and technology innovation
Required Qualifications ? Scientist: Master’s + 3+ years in Molecular Biology, Pharmacology, Neuroscience or related field. ? Senior Scientist: PhD 2+/MS + 6+ years in industry/academia. ? Expertise in: o Cell-based assay development (e.g., receptor signaling, functional phenotyping) o Molecular biology techniques (protein/RNA detection, gene editing) o Mammalian cell culture (primary neurons, glia, or iPSC-derived models) ? Proven ability to troubleshoot assays and analyze complex datasets
Preferred Qualifications ? Experience with CNS targets (e.g., neuroinflammation, neurodegeneration, blood-brain barrier models) ? Familiarity with automation/liquid handling systems ? Track record of contributions to preclinical drug development

工作地點(diǎn)

上海浦東新區(qū)ATLATL創(chuàng)新研發(fā)中心

職位發(fā)布者

劉薇/HR

三日內(nèi)活躍
立即溝通
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維泰瑞?。ū本┥锟萍加邢薰臼且患胰蛐缘膶W⒂谘邪l(fā)First-in-class化學(xué)藥物的生物制藥公司。該公司由北京生命科學(xué)研究所的所長(zhǎng),美國(guó)科學(xué)院院士,中國(guó)科學(xué)院外籍院士王曉東博士和北京生命科學(xué)研究所資深研究員張志遠(yuǎn)博士共同創(chuàng)建。公司坐落在昌平區(qū)中關(guān)村生命科學(xué)園。本公司針對(duì)王曉東博士在細(xì)胞凋亡、細(xì)胞程序性壞死等多種細(xì)胞死亡領(lǐng)域的原創(chuàng)性發(fā)現(xiàn)研發(fā)小分子抑制劑,致力于多種重大疾病的治療。這些抑制劑針對(duì)的疾病包括神經(jīng)退行性疾病如阿爾茲海默癥、多發(fā)性硬化癥、帕金森病等;缺血性疾病如腦卒中、腎缺血、心肌缺血;以及炎癥性疾病如腸炎、銀屑病、膿毒癥等。本公司研發(fā)能力涵蓋小分子篩選,化學(xué)合成,分子、細(xì)胞生物學(xué)研究,動(dòng)物藥效評(píng)價(jià),藥代藥動(dòng)分析及臨床前預(yù)毒理分析等藥物研發(fā)的所有環(huán)節(jié)。本公司的研發(fā)團(tuán)隊(duì)由王曉東博士和張志遠(yuǎn)博士直接領(lǐng)導(dǎo),團(tuán)隊(duì)主要成員均具備十年以上科學(xué)研究經(jīng)驗(yàn),前期科研成果均發(fā)表在國(guó)際頂級(jí)學(xué)術(shù)刊物如,Cell,Molecular Cell, eLife,PNAS等。本公司的管理團(tuán)隊(duì)均具備數(shù)十年國(guó)際制藥企業(yè)的管理經(jīng)驗(yàn),曾成功推動(dòng)多個(gè)藥物進(jìn)入臨床實(shí)驗(yàn)和上市使用。公司福利待遇:對(duì)于優(yōu)秀博士公司有機(jī)會(huì)解決北京戶口問(wèn)題;公司設(shè)有博士后工作站。
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