崗位職責(zé):
1、負(fù)責(zé)非臨床毒理學(xué)相關(guān)文獻(xiàn)與前沿技術(shù)的跟蹤、分析與評(píng)估,為項(xiàng)目決策提供科學(xué)依據(jù);
2、主導(dǎo)一般毒理試驗(yàn)的方案設(shè)計(jì)、過程協(xié)調(diào)、數(shù)據(jù)解讀與報(bào)告撰寫,確保研究全程符合GLP規(guī)范及科學(xué)性要求;
3、負(fù)責(zé)與國外客戶或?qū)<疫M(jìn)行良好的商務(wù)支持及技術(shù)交流工作;
4、負(fù)責(zé)組織臨床前毒理學(xué)部分IND申報(bào)資料的中英文撰寫與審核,支持國內(nèi)外注冊(cè)申報(bào)工作;
5、跟蹤國內(nèi)外(包括FDA、NMPA、ICH等)毒理學(xué)相關(guān)法規(guī)與指導(dǎo)原則更新,及時(shí)組織內(nèi)部分享與培訓(xùn),推動(dòng)技術(shù)體系持續(xù)優(yōu)化;
6、負(fù)責(zé)與委托方進(jìn)行臨床前研發(fā)等問題提供有效的技術(shù)支持;
7、完成上級(jí)領(lǐng)導(dǎo)安排的其他工作。
任職要求:
1、碩士及以上學(xué)歷,毒理學(xué)、藥理學(xué)等相關(guān)生物醫(yī)藥專業(yè),擁有5年以上非臨床GLP毒理工作經(jīng)驗(yàn),具備豐富的國外客戶項(xiàng)目交付和技術(shù)交流經(jīng)驗(yàn),曾在海外CRO公司任職者優(yōu)先;
2、具有較強(qiáng)的文獻(xiàn)調(diào)研及匯總能力,有熟練的英語聽說讀寫能力,能夠用流利的英語進(jìn)行技術(shù)交流;
3、熟悉FDA、NMPA及ICH等相關(guān)毒理學(xué)研究指導(dǎo)原則與GLP法規(guī);
4、系統(tǒng)掌握臨床前毒理學(xué)評(píng)價(jià)流程與研究設(shè)計(jì)方法;
5、具備較強(qiáng)的學(xué)習(xí)與整合能力、溝通協(xié)調(diào)能力、團(tuán)隊(duì)合作精神及責(zé)任心。
Duties & Responsibilities:
·Responsible for tracking, analyzing, and evaluating preclinical toxicology - related literature and cutting - edge technologies to provide a scientific basis for project decision - making.
·Lead the design of general toxicology study protocols, coordinate the research process, interpret data, and write reports, ensuring the entire research process complies with GLP (Good Laboratory Practice) standards and scientific requirements.
·Responsible for providing sound business support and conducting technical communications with foreign clients or experts.
·Responsible for organizing the writing and review of the preclinical toxicology section of IND application materials (both in Chinese and English) to support domestic and international registration and application work.
·Track updates to domestic and international (including FDA, NMPA, ICH (International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use)) toxicology - related regulations and guidelines, promptly organize internal sharing and training, and promote the continuous optimization of the technical system.
·Responsible for providing effective technical support to the client (contract giver) regarding preclinical R&D issues and other related matters.
Experience Requirements - Knowledge, Skills, & Abilities (KSAs):
·Master's degree or above in toxicology, pharmacology, or other related biomedicine fields.
·with more than 5 years of preclinical GLP toxicology work experience. Candidates should have rich experience in delivering projects for foreign clients and conducting technical communications with them, and those who have worked in overseas CRO (Contract Research Organization) companies will be given priority.
·Possess strong literature research and summary capabilities.
·Excellent written and oral communication skills in English as a must,and conduct technical communications in fluent English.
·Familiar with relevant toxicology research guidelines and GLP regulations of FDA, NMPA, ICH, etc.
·Have a systematic grasp of preclinical toxicology evaluation processes and study design methods.
·Possess strong learning and integration abilities, communication and coordination skills, team spirit, and a strong sense of responsibility.