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1. Position Details職位基本信息：
Position Title:
職位名稱: Bioanalytical Scientist (Associate/Senior Associate/Principal Associate) Division:部: China Innovation Center of Roche (CICoR)
工作地點: Shanghai Zhangjiang上海
2. Primary Purpose of Job (Job Summary)主要工作目標(biāo)（崗位簡介）
The individual will provide hands-on discovery bioanalytical support for small and large molecule discovery programs within the Pharmaceutical Sciences department in China Innovation Center of Roche (CICoR).
3. Principle Roles & Responsibilities / Accountabilities 主要職責(zé)/責(zé)任
(Major functions of the position) （職位的首要職能）
- Perform hand-on sample preparation for the analysis of selected in vivo and in vitro assay samples (particularly for protein or ADC qualitative and quantitative assays) using LC-HRMS and LC-Triple Quad MS/MS to support discovery programs.
- Perform hand-on sample analysis to profile in-house and competitor compounds including small molecule and large molecule compounds.
- Perform hand-on sample analysis for project specific biomarkers.
- Perform method development and qualification to ensure successful method transfer to CROs for bioanalysis-related activities.
- Perform data analysis and compile method development and sample analysis results. Write study report as needed.
- Conduct hand-on troubleshooting for bioanalytical issues.
- Other duties as assigned
4. Qualification and Experience 能力與經(jīng)驗
Education/Qualifications教育程度/所獲資格證書
● An individual with bachelor or master degree in life science with 0-5 years of working experience.
Key Skill / Knowledge Requirements
● Hand-on experience of bio-sample preparation including plasma, serum, cerebrospinal fluid and tissues. Working experience with regulatory bioanalysis is a plus.
● Training and/or experience with LC-MS/MS is required. Working experience with high resolution mass spectrometry (HRMS), e.g. Thermo Fisher Scientific Orbitrap, is preferred.
● Comfortable to work in a bilingual (English and Chinese) work environment.
● Strong organizational, communicational skills and ability to multi-tasking.
● Self-motivated and engaged learner.
● Experience and knowledge of GxP and regulatory guidance are optional.